From İstanbul to Ankara After than Ankara to Nevşehir Aksaray - Nevşehir - Uchisar - Goreme - Cavusin Anitta Cave Hotel or Kırşehirroad you can come (Kırşehir - Hacıbektaş - Avanos- Çavuşin -Anitta Cave Hotel.

From Adana: Pozantı - Niğde - Nevşehir - Uchisar - Goreme - Cavusin Anitta Cave Hotel
From Antalya: Manavgat - Akseki - Seydişehir - Konya - Aksaray - Nevşehir - Uchisar - Goreme - Cavusin Anitta Cave Hotel

There are regular buses from all major cities and holiday centers to Cappadpocia.
The bus companies are Nevşehirliler, Öncü Göreme, Metro. The transfers to/from the city center of Nevsehir and other towns in Cappadocia are handled free of charge by all the bus companies, you will need to check the information about your final destination on the bus once again.
Nevşehirliler Seyahat - 444 50 50
Öncü Göreme Turizm - 444 00 07
Metro Turizm - 444 34 55

There are regular domestic flights between İstanbul and two airports in Cappadocia, the Nevsehir and Kayseri airports. Nevsehir Airport is about half an hour and Kayseri airport is about 1 hour drive to Anitta Cave Hotel.

You can see the website of Airlines company.

THY
Pegasus